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化合物库

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Cat. No. Product Name
L4100 TGF-β/Smad靶点化合物库

184 compounds
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选;

化合物库

TGF-β/Smad靶点化合物库
Cat.No: L4100
Compounds: 184
Cat. No. Product Name Species Expression System
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II recep...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Transforming growth factor...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

TGF-β receptor type II,Tgfbr2,TGF...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant

transforming growth factor β-2,BS...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant

Latency-associated peptide,TGF-beta-3,Transform...

Human,Mouse,Rat HEK293 Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regu...
TMPJ-00314 ACVR2B Protein, Human, Recombinant (hFc & His)

ACVR2B,Activin Receptor Type IIB,...

Human HEK293 Cells
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, ...
TMPJ-00315 ACVR2A Protein, Human, Recombinant (hFc & His)

ACTR-IIA,Activin Receptor Type

Human HEK293 Cells
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors....
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant

TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-bet...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)...

重组蛋白

TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
Cat.No: TMPJ-00333
Species: Mouse
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
Cat.No: TMPJ-00334
Species: Mouse
Expression System: HEK293 Cells
TGF beta 2 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00261
Species: Mouse,Rat
Expression System: HEK293 Cells
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
Cat.No: TMPJ-00254
Species: Human,Mouse,Rat
Expression System: HEK293 Cells
ACVR2B Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00314
Species: Human
Expression System: HEK293 Cells
ACVR2A Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00315
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00771
Species: Mouse,Rat
Expression System: HEK293 Cells
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